Across 2,035 ranked games on patch 16.21 in Master and above, Aphelios mains win 53.2% of their games in the bot lane.
Their most common build appears in 37.3% of those games and wins 53.6% of its 759 games.
It starts 
two Health Potions and 
Doran's Bow, completes 
The Collector, 
Infinity Edge, 
Lord Dominik's Regards and 
Runaan's Hurricane in that order, and takes 
Gluttonous Greaves.
Three other builds are played often enough in the bot lane to be measured on their own.
In the bot lane, Aphelios mains fare best against 
Yunara (won 58.7% of 75 games), 
Ezreal (won 60.0% of 55 games) and 
Kai'Sa (won 55.9% of 111 games).
Their hardest matchups, the champions that counter Aphelios, are 
Yasuo (won 16.7% of 12 games), 
Samira (won 20.0% of 10 games) and 
Varus (won 37.7% of 53 games).